MNT antibody (AA 222-582) (APC)

Catalog No. ABIN8011517

This Rabbit Polyclonal antibody specifically detects MNT in FACS. It exhibits reactivity toward Human.

Quick Overview for MNT antibody (AA 222-582) (APC) (ABIN8011517)

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MNT antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-MNT Antibody (APC)

Binding Specificity: AA 222-582

Purpose: Anti-MNT Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MNT recombinant protein (Position: R222-A582).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MNT

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Alternative Name: MNT

Background:

Background: MNT (Max-binding protein MNT) is a Max-binding protein that is encoded by the MNT gene The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.

Gene Full Name: MAX network transcriptional repressor

Gene ID: 4335

UniProt: Q99583

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation