Monoamine Oxidase A antibody (N-Term) (Fluoro488)

Catalog No. ABIN8011633

The Fluoro488-conjugated Rabbit Polyclonal anti-Monoamine Oxidase A antibody (ABIN8011633) specifically detects Monoamine Oxidase A in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Monoamine Oxidase A antibody (N-Term) (Fluoro488) (ABIN8011633)

Target: Monoamine Oxidase A (MAOA)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Monoamine Oxidase A antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Monoamine Oxidase A Antibody (Fluoro488)

Binding Specificity: N-Term

Purpose: Anti-Monoamine Oxidase A/MAOA Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MAOA.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Monoamine Oxidase A

Target: Monoamine Oxidase A (MAOA)

Alternative Name: MAOA

Background:

Background: MAOA (Monoamine oxidase A), also known as AMINE OXIDASE (FLAVIN-CONTAINING) A, is an enzyme that in humans is encoded by the MAO-A gene. MAOA is an isozyme of monoamine oxidase which is also mapped on Xp11.3. MAOA degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the outer mitochondrial membrane. Mutation in MAOA results in monoamine oxidase deficiency, or Brunner syndrome. In humans, there is a 30-base repeat sequence repeated in one of several different numbers of times in the promoter region of the gene coding for MAOA. MAO-A levels in the brain as measured using positron emission tomography are elevated by an average of 34 % in patients with major depressive disorder. Inhibition of MAOA prevented apoptosis, and serum starvation of cortical brain cells from Maoa-deficient mice resulted in reduced apoptosis compared with wildtype mice.

Gene Full Name: monoamine oxidase A

Sequence Similarities: Belongs to the flavin monoamine oxidase family.

Gene ID: 4128

UniProt: P21397