Mps1 antibody (AA 487-821) (FITC)

Catalog No. ABIN8011713

The Rabbit Polyclonal anti-Mps1 antibody is suitable to detect Mps1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for Mps1 antibody (AA 487-821) (FITC) (ABIN8011713)

Target: Mps1 (TTK)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mps1 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-Mps1 Antibody (FITC)

Binding Specificity: AA 487-821

Purpose: Anti-TTK/Mps1/TTK Antibody FITC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TTK/Mps1/TTK recombinant protein (Position: Q487-S821).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Mps1

Target: Mps1 (TTK)

Alternative Name: TTK

Background:

Background: Dual specificity protein kinase TTK is a protein that in humans is encoded by the XRCC2 gene. This gene is mapped to 6q14.1. This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.

Gene Full Name: TTK protein kinase

Gene ID: 7272

UniProt: P33981