MUC5AC antibody (N-Term) (Biotin)

Catalog No. ABIN8011939

The Biotin-conjugated Rabbit Polyclonal anti-MUC5AC antibody (ABIN8011939) specifically detects MUC5AC in IHC, WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for MUC5AC antibody (N-Term) (Biotin) (ABIN8011939)

Target: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC5AC antibody is conjugated to Biotin

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Product Details anti-MUC5AC Antibody (Biotin)

Binding Specificity: N-Term

Purpose: Anti-Mucin 5AC/MUC5AC Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Mucin 5AC.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MUC5AC

Target: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Alternative Name: MUC5AC

Background:

Background: Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene. It is mapped to 11p15.5. MUC5AC is highly expressed in adult trachea and stomach. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease (COPD). It has been showed that activation of the NF-kappa-B signaling pathway by inflammatory cytokine TNF-alpha upregulated MUC5AC mRNA expression nearly 6-fold. MUC5AC is also a and critical mediator of resistance during intestinal nematode infection.

Gene Full Name: mucin 5AC, oligomeric mucus/gel-forming

Sequence Similarities: Contains 1 CTCK (C-terminal cystine knot-like) domain.

Gene ID: 4586

UniProt: P98088