MAL antibody (C-Term)

Catalog No. ABIN8012334

The Rabbit Polyclonal anti-MAL antibody is suitable to detect MAL in samples from Human. It has been validated for WB.

Quick Overview for MAL antibody (C-Term) (ABIN8012334)

Target: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAL antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-MAL Antibody

Binding Specificity: C-Term

Purpose: Anti-MAL Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse,rat sequences.

Characteristics: Anti-MAL Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MAL, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MAL

Target: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Alternative Name: MAL

Background:

Background: Myelin and lymphocyte protein is a protein that in humans is encoded by the MAL gene. The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.

Gene Full Name: mal, T cell differentiation protein (MAL blood group)

Molecular Weight: 17 kDa

Gene ID: 4118

UniProt: P21145

Pathways: Asymmetric Protein Localization