MOG antibody (Middle Region) (APC)

Catalog No. ABIN8012386

The APC-conjugated Rabbit Polyclonal anti-MOG antibody (ABIN8012386) specifically detects MOG in FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for MOG antibody (Middle Region) (APC) (ABIN8012386)

Target: MOG (Myelin Oligodendrocyte Glycoprotein (MOG))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MOG antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-MOG Antibody (APC)

Binding Specificity: Middle Region

Purpose: Anti-Myelin oligodendrocyte glycoprotein/MOG Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Myelin oligodendrocyte glycoprotein/MOG, which shares 85.7% and 88.6% amino acid (aa) sequence identity with mouse and rat Myelin oligodendrocyte glycoprotein/MOG, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MOG

Target: MOG (Myelin Oligodendrocyte Glycoprotein (MOG))

Alternative Name: MOG

Background:

Background: Myelin oligodendrocyte glycoprotein (MOG) is a glycoprotein believed to be important in the myelination of nerves in the central nervous system (CNS). In humans this protein is encoded by the MOG gene. This gene is mapped to 6p22.1. It is speculated to serve as a necessary adhesion molecule to provide structural integrity to the myelin sheath and is known to develop late on the oligodendrocyte. The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Full Name: myelin oligodendrocyte glycoprotein

Gene ID: 4340

UniProt: Q16653