Myeloperoxidase antibody (AA 556-697)
Quick Overview for Myeloperoxidase antibody (AA 556-697) (ABIN8012488)
Target
See all Myeloperoxidase (MPO) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
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Binding Specificity
- AA 556-697
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Purpose
- Anti-MPO Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Characteristics
- Anti-MPO Antibody. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human MPO recombinant protein (Position: K556-I697).
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Isotype
- IgG
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Application Notes
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Expiry Date
- 12 months
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- Myeloperoxidase (MPO)
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Alternative Name
- MPO
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Background
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Background: Myeloperoxidase (MPO) is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. It is located in the nucleus as well as in the cytoplasm. Intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function. The standard product used in this kit is the product of gene recombination, consisting of 697(A49-S745) amino acids with the molecular mass of 80KDa.
Gene Full Name: myeloperoxidase
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Molecular Weight
- 55 kDa, 80-90 kDa
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Gene ID
- 4353
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UniProt
- P05164
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Pathways
- Chromatin Binding
Target
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