Myeloperoxidase antibody (C-Term) (Fluoro647)

Catalog No. ABIN8012498

This Rabbit Polyclonal antibody specifically detects Myeloperoxidase in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Myeloperoxidase antibody (C-Term) (Fluoro647) (ABIN8012498)

Target: Myeloperoxidase (MPO)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myeloperoxidase antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Myeloperoxidase Antibody (Fluoro647)

Binding Specificity: C-Term

Purpose: Anti-Myeloperoxidase/MPO Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse,rat sequences by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MPO, different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Myeloperoxidase

Target: Myeloperoxidase (MPO)

Alternative Name: MPO

Background:

Background: Myeloperoxidase (MPO) is a mammalian phagocyte hemoprotein though to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. It is located in the nucleus as well as in the cytoplasm. Intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function.

Gene Full Name: myeloperoxidase

Sequence Similarities: Belongs to the peroxidase family. XPO subfamily.

UniProt: P05164

Pathways: Chromatin Binding