Myoferlin antibody (AA 175-2003) (Fluoro550)

Catalog No. ABIN8012569

The Fluoro550-conjugated Rabbit Polyclonal anti-Myoferlin antibody (ABIN8012569) specifically detects Myoferlin in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Myoferlin antibody (AA 175-2003) (Fluoro550) (ABIN8012569)

Target: Myoferlin (MYOF)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myoferlin antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-Myoferlin Antibody (Fluoro550)

Binding Specificity: AA 175-2003

Purpose: Anti-MYOF Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human MYOF shares 93.9% amino acid (aa) sequence identity with mouse MYOF.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MYOF recombinant protein (Position: E175-E2003). Human MYOF shares 93.9% amino acid (aa) sequence identity with mouse MYOF.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Myoferlin

Target: Myoferlin (MYOF)

Alternative Name: MYOF

Background:

Background: Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.

Gene Full Name: myoferlin

Gene ID: 26509

UniProt: Q9NZM1