Myoferlin antibody (AA 175-2003)

Catalog No. ABIN8012576

This Rabbit Polyclonal antibody specifically detects Myoferlin in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Myoferlin antibody (AA 175-2003) (ABIN8012576)

Target: Myoferlin (MYOF)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myoferlin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-Myoferlin Antibody

Binding Specificity: AA 175-2003

Purpose: Anti-MYOF Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human MYOF shares 93.9% amino acid (aa) sequence identity with mouse MYOF.

Characteristics: Anti-MYOF Antibody. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MYOF recombinant protein (Position: E175-E2003). Human MYOF shares 93.9% amino acid (aa) sequence identity with mouse MYOF.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Myoferlin

Target: Myoferlin (MYOF)

Alternative Name: MYOF

Background:

Background: Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.

Gene Full Name: myoferlin

Molecular Weight: 250 kDa

Gene ID: 26509

UniProt: Q9NZM1