MYBPC3 antibody (AA 1070-1123)

Catalog No. ABIN8012665

The Rabbit Polyclonal anti-MYBPC3 antibody (ABIN8012665) specifically detects MYBPC3 in WB, ELISA and IHC. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for MYBPC3 antibody (AA 1070-1123) (ABIN8012665)

Target: MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYBPC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Grade: Carrier-free

Product Details anti-MYBPC3 Antibody

Binding Specificity: AA 1070-1123

Purpose: Anti-MYBPC3 Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-MYBPC3 Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human MYBPC3 recombinant protein (Position: Q1070-H1123).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MYBPC3

Target: MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))

Alternative Name: MYBPC3

Background:

Background: The myosin-binding protein C, cardiac-type is a protein that in humans is encode by the MYBPC3 gene. MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.

Gene Full Name: myosin binding protein C3

Molecular Weight: 160 kDa

Gene ID: 4607

UniProt: Q14896