MYO1E antibody (AA 221-1065) (Fluoro550)

Catalog No. ABIN8012713

The Fluoro550-conjugated Rabbit Polyclonal anti-MYO1E antibody (ABIN8012713) specifically detects MYO1E in FACS. The antibody is reactive with Human samples.

Quick Overview for MYO1E antibody (AA 221-1065) (Fluoro550) (ABIN8012713)

Target: MYO1E (Myosin IE (MYO1E))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYO1E antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-MYO1E Antibody (Fluoro550)

Binding Specificity: AA 221-1065

Purpose: Anti-MYO1E Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human MYO1E shares 95.9%,95.3% amino acid (aa) sequence identity with mouse,rat MYO1E,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MYO1E recombinant protein (Position: A221-Q1065). Human MYO1E shares 95.9% and 95.3% amino acid (aa) sequence identity with mouse and rat MYO1E, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MYO1E

Target: MYO1E (Myosin IE (MYO1E))

Alternative Name: MYO1E

Background:

Background: This gene encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. This gene has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17.

Gene Full Name: myosin IE

Gene ID: 4643

UniProt: Q12965

Pathways: Platelet-derived growth Factor Receptor Signaling