Myotilin antibody (AA 9-494) (Biotin)

Catalog No. ABIN8012875

The Biotin-conjugated Rabbit Polyclonal anti-Myotilin antibody (ABIN8012875) specifically detects Myotilin in WB, IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Myotilin antibody (AA 9-494) (Biotin) (ABIN8012875)

Target: Myotilin (MYOT)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myotilin antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Myotilin Antibody (Biotin)

Binding Specificity: AA 9-494

Purpose: Anti-MYOT Antibody Biotin Conjugated

Predicted Reactivity: Human MYOT shares 88.9% amino acid (aa) sequence identity with mouse MYOT.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MYOT recombinant protein (Position: H9-E494). Human MYOT shares 88.9% amino acid (aa) sequence identity with mouse MYOT.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Myotilin

Target: Myotilin (MYOT)

Alternative Name: MYOT

Background:

Background: Myotilin is a protein that in humans is encoded by the MYOT gene. This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Gene Full Name: myotilin

Gene ID: 9499

UniProt: Q9UBF9