MTMR2 antibody (N-Term) (Cy3)

Catalog No. ABIN8012898

The Rabbit Polyclonal anti-MTMR2 antibody is suitable to detect MTMR2 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for MTMR2 antibody (N-Term) (Cy3) (ABIN8012898)

Target: MTMR2 (Myotubularin Related Protein 2 (MTMR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTMR2 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-MTMR2 Antibody (Cy3)

Binding Specificity: N-Term

Purpose: Anti-MTMR2 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MTMR2, identical to the related mouse sequences.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MTMR2

Target: MTMR2 (Myotubularin Related Protein 2 (MTMR2))

Alternative Name: MTMR2

Background:

Background: Myotubularin-related protein 2 also known as phosphatidylinositol-3,5-bisphosphate 3-phosphatase or phosphatidylinositol-3-phosphate phosphatase is a protein that in humans is encoded by the MTMR2 gene. This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene.

Gene Full Name: myotubularin related protein 2

Gene ID: 8898

UniProt: Q13614

Pathways: Inositol Metabolic Process, Synaptic Membrane