NDC80 antibody (AA 87-602) (Fluoro647)

Catalog No. ABIN8014029

The Rabbit Polyclonal anti-NDC80 antibody is suitable to detect NDC80 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for NDC80 antibody (AA 87-602) (Fluoro647) (ABIN8014029)

Target: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDC80 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-NDC80 Antibody (Fluoro647)

Binding Specificity: AA 87-602

Purpose: Anti-HEC1/HEC/NDC80 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HEC1/HEC/NDC80 recombinant protein (Position: N87-E602).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NDC80

Target: NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

Alternative Name: NDC80

Background:

Background: Kinetochore protein NDC80 homolog is a protein that in humans is encoded by the NDC80 gene. It is mapped to 18p11.32. This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.

Gene Full Name: NDC80 kinetochore complex component

Gene ID: 10403

UniProt: O14777

Pathways: Maintenance of Protein Location