Nebulette antibody (AA 86-842) (Fluoro647)

Catalog No. ABIN8014095

The Rabbit Polyclonal anti-Nebulette antibody is suitable to detect Nebulette in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for Nebulette antibody (AA 86-842) (Fluoro647) (ABIN8014095)

Target: Nebulette (NEBL)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nebulette antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Nebulette Antibody (Fluoro647)

Binding Specificity: AA 86-842

Purpose: Anti-NEBL Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NEBL recombinant protein (Position: E86-K842).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Nebulette

Target: Nebulette (NEBL)

Alternative Name: NEBL

Background:

Background: Nebulette is a cardiac-specific isoform belonging to the nebulin family of proteins. It is encoded by the NEBL gene. This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants.

Gene Full Name: nebulette

Gene ID: 10529

UniProt: O76041