nectin-3 antibody (AA 92-296) (Biotin)

Catalog No. ABIN8014108

The Biotin-conjugated Rabbit Polyclonal anti-nectin-3 antibody (ABIN8014108) specifically detects nectin-3 in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for nectin-3 antibody (AA 92-296) (Biotin) (ABIN8014108)

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This nectin-3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-nectin-3 Antibody (Biotin)

Binding Specificity: AA 92-296

Purpose: Anti-Nectin 3/NECTIN3 Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Nectin 3/NECTIN3 recombinant protein (Position: E92-N296).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for nectin-3

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Alternative Name: NECTIN3

Background:

Background: Nectin-3, also known as poliovirus receptor-related 3, is a 95 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. It is mapped to 3q13.13. This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of ional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.

Gene Full Name: nectin cell adhesion molecule 3

Gene ID: 25945

UniProt: Q9NQS3

Pathways: Cell-Cell Junction Organization