Neurexin 2 (NRXN2) (N-Term) antibody (Fluoro594)

Catalog No. ABIN8014574

This Rabbit Polyclonal antibody specifically detects Neurexin 2 in FACS. It exhibits reactivity toward Rat and Mouse.

Quick Overview for Neurexin 2 (NRXN2) (N-Term) antibody (Fluoro594) (ABIN8014574)

Target: Neurexin 2 (NRXN2)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Fluoro594

Application: Flow Cytometry (FACS)

Product Details

Binding Specificity: N-Term

Purpose: Anti-NRXN2 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human NRXN2 shares 100% amino acid (aa) sequence identity with both mouse,rat NRXN2.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human NRXN2. Human NRXN2 shares 100% amino acid (aa) sequence identity with both mouse and rat NRXN2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details

Target: Neurexin 2 (NRXN2)

Alternative Name: NRXN2

Background:

Background: This gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992).

Gene Full Name: neurexin 2

Gene ID: 9379

UniProt: P58401

Pathways: Synaptic Membrane