Neurexin 2 (NRXN2) (N-Term) antibody

Catalog No. ABIN8014580

This Rabbit Polyclonal antibody specifically detects Neurexin 2 in WB. It exhibits reactivity toward Rat and Mouse.

Quick Overview for Neurexin 2 (NRXN2) (N-Term) antibody (ABIN8014580)

Target: Neurexin 2 (NRXN2)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details

Binding Specificity: N-Term

Purpose: Anti-NRXN2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human NRXN2 shares 100% amino acid (aa) sequence identity with both mouse,rat NRXN2.

Characteristics: Anti-NRXN2 Antibody. Tested in WB applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human NRXN2. Human NRXN2 shares 100% amino acid (aa) sequence identity with both mouse and rat NRXN2.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: Neurexin 2 (NRXN2)

Alternative Name: NRXN2

Background:

Background: This gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992).

Gene Full Name: neurexin 2

Molecular Weight: 185 kDa

Gene ID: 9379

UniProt: P58401

Pathways: Synaptic Membrane