Neurexin 3 antibody (AA 294-549) (APC)

Catalog No. ABIN8014588

The APC-conjugated Rabbit Polyclonal anti-Neurexin 3 antibody (ABIN8014588) specifically detects Neurexin 3 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Neurexin 3 antibody (AA 294-549) (APC) (ABIN8014588)

Target: Neurexin 3 (NRXN3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurexin 3 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Neurexin 3 Antibody (APC)

Binding Specificity: AA 294-549

Purpose: Anti-NRXN3 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NRXN3 recombinant protein (Position: R294-P549).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Neurexin 3

Target: Neurexin 3 (NRXN3)

Alternative Name: NRXN3

Background:

Background: Neurexin-3-alpha is a protein that in humans is encoded by the NRXN3 gene. This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder.

Gene Full Name: neurexin 3

Gene ID: 9369

UniProt: Q9HDB5