Neurogranin antibody (AA 11-54) (Fluoro647)

Catalog No. ABIN8014799

This Rabbit Polyclonal antibody specifically detects Neurogranin in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Neurogranin antibody (AA 11-54) (Fluoro647) (ABIN8014799)

Target: Neurogranin (NRGN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurogranin antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Neurogranin Antibody (Fluoro647)

Binding Specificity: AA 11-54

Purpose: Anti-Neurogranin/NRGN Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NRGN recombinant protein (Position: K11-K54).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Neurogranin

Target: Neurogranin (NRGN)

Alternative Name: NRGN

Background:

Background: Neurogranin is a calmodulin-binding protein expressed primarily in the brain, particularly in dendritic spines, and participating in the protein kinase C signaling pathway. Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.

Gene Full Name: neurogranin

Gene ID: 4900

UniProt: Q92686