Neuromedin U antibody (C-Term) (Fluoro488)

Catalog No. ABIN8014836

The Rabbit Polyclonal anti-Neuromedin U antibody is suitable to detect Neuromedin U in samples from Rat and Mouse. It has been validated for FACS.

Quick Overview for Neuromedin U antibody (C-Term) (Fluoro488) (ABIN8014836)

Target: Neuromedin U (NMU)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuromedin U antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Neuromedin U Antibody (Fluoro488)

Binding Specificity: C-Term

Purpose: Anti-NMU Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human NMU, which shares 64% and 56% amino acid (aa) sequence identity with mouse and rat NMU, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Neuromedin U

Target: Neuromedin U (NMU)

Alternative Name: NMU

Background:

Background: Neuromedin U (NMU) is a neuropeptide with potent activity on smooth muscle, which was isolated first from porcine spinal cord and later from other species. It is a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide.

Gene Full Name: neuromedin U

Gene ID: 10874

UniProt: P48645

Pathways: Feeding Behaviour, Photoperiodism