NrCAM antibody (AA 207-1025) (HRP)

Catalog No. ABIN8014884

The Rabbit Polyclonal anti-NrCAM antibody is suitable to detect NrCAM in samples from Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for NrCAM antibody (AA 207-1025) (HRP) (ABIN8014884)

Target: NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NrCAM antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NrCAM Antibody (HRP)

Binding Specificity: AA 207-1025

Purpose: Anti-NRCAM Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse NRCAM shares 91.7%,97.1% amino acid (aa) sequence identity with human,rat NRCAM,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NRCAM recombinant protein (Position: R207-Q1025). Mouse NRCAM shares 91.7% and 97.1% amino acid (aa) sequence identity with human and rat NRCAM, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NrCAM

Target: NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))

Alternative Name: NRCAM

Background:

Background: Enables protein binding activity involved in heterotypic cell-cell adhesion. Involved in cell-cell adhesion, nervous system development, and regulation of postsynapse organization. Acts upstream of or within several processes, including neuron development, neuronal action potential propagation, and regulation of neuron projection development. Located in axon, plasma membrane, and synapse. Is active in glutamatergic synapse and postsynaptic density membrane. Is expressed in several structures, including alimentary system, central nervous system, genitourinary system, integumental system, and sensory organ. Used to study autism spectrum disorder. Orthologous to human NRCAM (neuronal cell adhesion molecule).

Gene Full Name: neuronal cell adhesion molecule

Gene ID: 319504

UniProt: Q810U4

Pathways: Regulation of Cell Size