Neuropilin 1 antibody (AA 521-827)

Catalog No. ABIN8015108

This Rabbit Polyclonal antibody specifically detects Neuropilin 1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Neuropilin 1 antibody (AA 521-827) (ABIN8015108)

Target: Neuropilin 1 (NRP1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuropilin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-Neuropilin 1 Antibody

Binding Specificity: AA 521-827

Purpose: Anti-Neuropilin 1/NRP1 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Anti-Neuropilin 1/NRP1 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Neuropilin 1/NRP1 recombinant protein (Position: N521-T827).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Neuropilin 1

Target: Neuropilin 1 (NRP1)

Alternative Name: NRP1

Background:

Background: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contain a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Gene Full Name: neuropilin 1

Molecular Weight: 140 kDa

Gene ID: 8829

UniProt: O14786

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals