Neurturin antibody (AA 1-197) (Biotin)

Catalog No. ABIN8015241

The Rabbit Polyclonal anti-Neurturin antibody is suitable to detect Neurturin in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for Neurturin antibody (AA 1-197) (Biotin) (ABIN8015241)

Target: Neurturin (NRTN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurturin antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Neurturin Antibody (Biotin)

Binding Specificity: AA 1-197

Purpose: Anti-NRTN Antibody Biotin Conjugated

Predicted Reactivity: Human Neurturin,NRTN shares 86.3% amino acid (aa) sequence identity with mouse Neurturin,NRTN.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Neurturin/NRTN recombinant protein (Position: M1-V197). Human Neurturin/NRTN shares 86.3% amino acid (aa) sequence identity with mouse Neurturin/NRTN.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Neurturin

Target: Neurturin (NRTN)

Alternative Name: NRTN

Background:

Background: Neurturin (NRTN) is a protein that is encoded in humans by the NRTN gene. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease.

Gene Full Name: neurturin

Gene ID: 4902

UniProt: Q99748