NSMAF antibody (AA 51-868) (Biotin)

Catalog No. ABIN8015263

The Biotin-conjugated Rabbit Polyclonal anti-NSMAF antibody (ABIN8015263) specifically detects NSMAF in WB, IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NSMAF antibody (AA 51-868) (Biotin) (ABIN8015263)

Target: NSMAF (Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSMAF antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-NSMAF Antibody (Biotin)

Binding Specificity: AA 51-868

Purpose: Anti-NSMAF Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human NSMAF shares 92.3% amino acid (aa) sequence identity with mouse NSMAF.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NSMAF recombinant protein (Position: K51-L868). Human NSMAF shares 92.3% amino acid (aa) sequence identity with mouse NSMAF.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NSMAF

Target: NSMAF (Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF))

Alternative Name: NSMAF

Background:

Background: This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.

Gene Full Name: neutral sphingomyelinase activation associated factor

Gene ID: 8439

UniProt: Q92636