NMNAT1 antibody (AA 56-279)
Quick Overview for NMNAT1 antibody (AA 56-279) (ABIN8015482)
Target
See all NMNAT1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
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Binding Specificity
- AA 56-279
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Purpose
- Anti-NMNAT1 Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins
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Predicted Reactivity
- Human NMNAT1 shares 81.2% amino acid (aa) sequence identity with mouse NMNAT1.
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Characteristics
- Anti-NMNAT1 Antibody. Tested in WB, IHC, IF, ICC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human NMNAT1 recombinant protein (Position: K56-T279). Human NMNAT1 shares 81.2% amino acid (aa) sequence identity with mouse NMNAT1.
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Isotype
- IgG
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Application Notes
- Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Expiry Date
- 12 months
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- NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))
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Alternative Name
- NMNAT1
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Background
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Background: This gene encodes an enzyme which catalyzes a key step in the biosynthesis of nicotinamide adenine dinucleotide (NAD). The encoded enzyme is one of several nicotinamide nucleotide adenylyltransferases, and is specifically localized to the cell nucleus. Activity of this protein leads to the activation of a nuclear deacetylase that functions in the protection of damaged neurons. Mutations in this gene have been associated with Leber congenital amaurosis 9. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14, and 15.
Gene Full Name: nicotinamide nucleotide adenylyltransferase 1
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Molecular Weight
- 28 kDa
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Gene ID
- 64802
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UniProt
- Q9HAN9
Target
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