NPRL2 antibody (AA 90-380) (PE)

Catalog No. ABIN8015744

This Rabbit Polyclonal antibody specifically detects NPRL2 in FACS. It exhibits reactivity toward Mouse and Rat.

Quick Overview for NPRL2 antibody (AA 90-380) (PE) (ABIN8015744)

Target: NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPRL2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-NPRL2 Antibody (PE)

Binding Specificity: AA 90-380

Purpose: Anti-NPRL2 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human NPRL2 shares 98.3% amino acid (aa) sequence identity with mouse NPRL2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NPRL2 recombinant protein (Position: D90-K380). Human NPRL2 shares 98.3% amino acid (aa) sequence identity with mouse NPRL2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NPRL2

Target: NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))

Alternative Name: NPRL2

Background:

Background: Nitrogen permease regulator 2-like protein (NPRL2) also known as tumor suppressor candidate 4 (TUSC4) is a protein that in humans is encoded by the NPRL2 gene. Enables GTPase activator activity. Involved in cellular response to amino acid starvation, negative regulation of TORC1 signaling, and negative regulation of kinase activity. Part of GATOR1 complex. Is active in lysosomal membrane. Implicated in familial focal epilepsy with variable foci 2.

Gene Full Name: NPR2 like, GATOR1 complex subunit

Gene ID: 10641

UniProt: Q8WTW4