NLRP4G antibody (C-Term) (Fluoro550)

Catalog No. ABIN8015904

The Rabbit Polyclonal anti-NLRP4G antibody is suitable to detect NLRP4G in samples from Mouse. It has been validated for FACS.

Quick Overview for NLRP4G antibody (C-Term) (Fluoro550) (ABIN8015904)

Target: NLRP4G (NLR Family, Pyrin Domain Containing 4G (NLRP4G))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP4G antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-NLRP4G Antibody (Fluoro550)

Binding Specificity: C-Term

Purpose: Anti-NLRP4G Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse NLRP4G.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NLRP4G

Target: NLRP4G (NLR Family, Pyrin Domain Containing 4G (NLRP4G))

Alternative Name: Nlrp4g

Background:

Background: Stra8, stimulated by retinoic acid 8, is expressed in embryonic ovaries just before meiotic initiation, whereas in testis it is expressed after birth. The STRA8 gene contains 9 exons. And this gene is mapped to chromosome 7q31. Retinoic acid (RA) signaling was required for Stra8 expression, and therefore initiation of meiosis, in embryonic mouse ovaries. RA was sufficient to induce Stra8 expression in embryonic testis. Cyp26-mediated RA metabolism was responsible for delaying Stra8 expression in embryonic testis. Since RA signaling regulated Stra8 expression in both embryonic ovaries and adult testis, it was said this portion of the meiotic initiation pathway may be identical in both sexes.

Gene Full Name: NLR family, pyrin domain containing 4G

Sequence Similarities: Contains DAPIN domain.

Gene ID: 235779

UniProt: Q66JP4