NSUN4 antibody (AA 1-379)

Catalog No. ABIN8015999

This Rabbit Polyclonal antibody specifically detects NSUN4 in ELISA and WB. It exhibits reactivity toward Human.

Quick Overview for NSUN4 antibody (AA 1-379) (ABIN8015999)

Target: NSUN4 (NOL1/NOP2/Sun Domain Family, Member 4 (NSUN4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSUN4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Grade: Carrier-free

Product Details anti-NSUN4 Antibody

Binding Specificity: AA 1-379

Purpose: Anti-NSUN4 Antibody

Predicted Reactivity: Human NSUN4 shares 86.3% amino acid (aa) sequence identity with mouse NSUN4.

Characteristics: Anti-NSUN4 Antibody. Tested in WB, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NSUN4 recombinant protein (Position: M1-K379). Human NSUN4 shares 86.3% amino acid (aa) sequence identity with mouse NSUN4.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NSUN4

Target: NSUN4 (NOL1/NOP2/Sun Domain Family, Member 4 (NSUN4))

Alternative Name: NSUN4

Background:

Background: NSUN4 belongsto a family of RNA 5-methylcytosine (m5C) methyltransferases(MTases).MTERF4 recruits NSUN4 to the large ribosomal subunit in a process crucial for mitochondrial ribosome biogenesis. NSUN4 is a dual function protein, which on the one hand is needed for 12S rRNA methylation, and on the other hand interacts withMTERF4 to facilitate mitoribosomal assembly. The calculatedMWof NSUN4 is 43 kDa, 29786-1-AP can detect the band around 40 kDa.

Gene Full Name: NOP2/Sun RNA methyltransferase 4

Molecular Weight: 40 kDa

Gene ID: 387338

UniProt: Q96CB9