NSUN3 antibody (AA 12-310) (FITC)

Catalog No. ABIN8016116

This Rabbit Polyclonal antibody specifically detects NSUN3 in FACS. It exhibits reactivity toward Human and Monkey.

Quick Overview for NSUN3 antibody (AA 12-310) (FITC) (ABIN8016116)

Target: NSUN3 (NOP2/Sun Domain Family, Member 3 (NSUN3))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSUN3 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-NSUN3 Antibody (FITC)

Binding Specificity: AA 12-310

Purpose: Anti-NSUN3 Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NSUN3 recombinant protein (Position: K12-E310).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NSUN3

Target: NSUN3 (NOP2/Sun Domain Family, Member 3 (NSUN3))

Alternative Name: NSUN3

Background:

Background: NSUN3 (NOL1/NOP2/Sun domain family, member 3), also known as MST077, is a 340 amino acid protein that belongs to the methyltransferase superfamily and is thought to function as an S-adenosyl-L-methionine-dependent methyltransferase. The gene encoding NSUN3 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3

Gene Full Name: NOP2/Sun RNA methyltransferase 3

Gene ID: 63899

UniProt: Q9H649