NSUN3 antibody (AA 12-310) (HRP)

Catalog No. ABIN8016117

The Rabbit Polyclonal anti-NSUN3 antibody is suitable to detect NSUN3 in samples from Human and Monkey. It has been validated for WB, ELISA and IHC.

Quick Overview for NSUN3 antibody (AA 12-310) (HRP) (ABIN8016117)

Target: NSUN3 (NOP2/Sun Domain Family, Member 3 (NSUN3))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSUN3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NSUN3 Antibody (HRP)

Binding Specificity: AA 12-310

Purpose: Anti-NSUN3 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NSUN3 recombinant protein (Position: K12-E310).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NSUN3

Target: NSUN3 (NOP2/Sun Domain Family, Member 3 (NSUN3))

Alternative Name: NSUN3

Background:

Background: NSUN3 (NOL1/NOP2/Sun domain family, member 3), also known as MST077, is a 340 amino acid protein that belongs to the methyltransferase superfamily and is thought to function as an S-adenosyl-L-methionine-dependent methyltransferase. The gene encoding NSUN3 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3

Gene Full Name: NOP2/Sun RNA methyltransferase 3

Gene ID: 63899

UniProt: Q9H649