NCOA4 antibody (AA 14-614) (FITC)

Catalog No. ABIN8016809

This Rabbit Polyclonal antibody specifically detects NCOA4 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NCOA4 antibody (AA 14-614) (FITC) (ABIN8016809)

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOA4 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-NCOA4 Antibody (FITC)

Binding Specificity: AA 14-614

Purpose: Anti-NCOA4 Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NCOA4 recombinant protein (Position: R14-M614).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NCOA4

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Alternative Name: NCOA4

Background:

Background: Nuclear receptor coactivator 4 is a protein that in humans is encoded by the NCOA4 gene. This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.

Gene Full Name: nuclear receptor coactivator 4

Gene ID: 8031

UniProt: Q13772

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway