NCOA6 antibody (AA 64-1475) (Biotin)

Catalog No. ABIN8016826

The Biotin-conjugated Rabbit Polyclonal anti-NCOA6 antibody (ABIN8016826) specifically detects NCOA6 in ELISA, WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NCOA6 antibody (AA 64-1475) (Biotin) (ABIN8016826)

Target: NCOA6 (Nuclear Receptor Coactivator 6 (NCOA6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOA6 antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NCOA6 Antibody (Biotin)

Binding Specificity: AA 64-1475

Purpose: Anti-NCOA6 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human NCOA6 shares 92.1% amino acid (aa) sequence identity with mouse NCOA6.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NCOA6 recombinant protein (Position: K64-E1475). Human NCOA6 shares 92.1% amino acid (aa) sequence identity with mouse NCOA6.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NCOA6

Target: NCOA6 (Nuclear Receptor Coactivator 6 (NCOA6))

Alternative Name: NCOA6

Background:

Background: The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: nuclear receptor coactivator 6

Gene ID: 23054

UniProt: Q14686

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha