NRF1 antibody (AA 246-503) (APC)
Quick Overview for NRF1 antibody (AA 246-503) (APC) (ABIN8017064)
Target
See all NRF1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 246-503
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Purpose
- Anti-NRF1 Antibody APC Conjugated
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Specificity
- No cross reactivity with other proteins.
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Purification
- Immunogen affinity purified.
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Immunogen
- E. coli-derived human NRF1 recombinant protein (Position: D246-Q503).
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Isotype
- IgG
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Application Notes
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Expiry Date
- 12 months
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- NRF1 (Nuclear Respiratory Factor 1 (NRF1))
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Alternative Name
- NRF1
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Background
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Background: Nuclear respiratory factor 1, is also known as NRF1. This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for nuclear factor (erythroid-derived 2)-like 1 which has an official symbol of NFE2L1.
Gene Full Name: nuclear respiratory factor 1
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Gene ID
- 4899
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UniProt
- Q16656
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Pathways
- Regulation of Lipid Metabolism by PPARalpha
Target
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