NUP50 antibody (Middle Region) (Fluoro550)

Catalog No. ABIN8017347

The Rabbit Polyclonal anti-NUP50 antibody is suitable to detect NUP50 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for NUP50 antibody (Middle Region) (Fluoro550) (ABIN8017347)

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP50 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-NUP50 Antibody (Fluoro550)

Binding Specificity: Middle Region

Purpose: Anti-NUP50 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human NUP50 shares 95.7% amino acid (aa) sequence identity with mouse NUP50.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human NUP50. Human NUP50 shares 95.7% amino acid (aa) sequence identity with mouse NUP50.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NUP50

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Alternative Name: NUP50

Background:

Background: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: nucleoporin 50

Gene ID: 10762

UniProt: Q9UKX7

Pathways: Tube Formation