TPR antibody (Middle Region) (HRP)

Catalog No. ABIN8017460

This Rabbit Polyclonal antibody specifically detects TPR in WB, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TPR antibody (Middle Region) (HRP) (ABIN8017460)

Target: TPR (Nucleoprotein TPR (TPR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPR antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-TPR Antibody (HRP)

Binding Specificity: Middle Region

Purpose: Anti-TPR Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human TPR, which shares 89.7% and 93.1% amino acid (aa) sequence identity with mouse and rat TPR, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TPR

Target: TPR (Nucleoprotein TPR (TPR))

Alternative Name: TPR

Background:

Background: The tetratricopeptide repeat (TPR) is a structural motif. This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein ly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.

Gene Full Name: translocated promoter region, nuclear basket protein

Gene ID: 7175

UniProt: P12270