TPR antibody (N-Term) (Fluoro550)

Catalog No. ABIN8017468

The Fluoro550-conjugated Rabbit Polyclonal anti-TPR antibody (ABIN8017468) specifically detects TPR in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TPR antibody (N-Term) (Fluoro550) (ABIN8017468)

Target: TPR (Nucleoprotein TPR (TPR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPR antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-TPR Antibody (Fluoro550)

Binding Specificity: N-Term

Purpose: Anti-TPR Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human TPR, which shares 90.6% amino acid (aa) sequence identity with mouse and rat TPR.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TPR

Target: TPR (Nucleoprotein TPR (TPR))

Alternative Name: TPR

Background:

Background: The tetratricopeptide repeat (TPR) is a structural motif. This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein ly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.

Gene Full Name: translocated promoter region, nuclear basket protein

Gene ID: 7175

UniProt: P12270