TPR antibody (N-Term)

Catalog No. ABIN8017475

This Rabbit Polyclonal antibody specifically detects TPR in WB, IHC, FACS, ICC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TPR antibody (N-Term) (ABIN8017475)

Target: TPR (Nucleoprotein TPR (TPR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Grade: Carrier-free

Product Details anti-TPR Antibody

Binding Specificity: N-Term

Purpose: Anti-TPR Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-TPR Antibody. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human TPR, which shares 90.6% amino acid (aa) sequence identity with mouse and rat TPR.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TPR

Target: TPR (Nucleoprotein TPR (TPR))

Alternative Name: TPR

Background:

Background: The tetratricopeptide repeat (TPR) is a structural motif. This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein ly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.

Gene Full Name: translocated promoter region, nuclear basket protein

Molecular Weight: 267 kDa

Gene ID: 7175

UniProt: P12270