NUBP1 antibody (AA 1-311) (PE)

Catalog No. ABIN8017550

This Rabbit Polyclonal antibody specifically detects NUBP1 in FACS. It exhibits reactivity toward Human.

Quick Overview for NUBP1 antibody (AA 1-311) (PE) (ABIN8017550)

Target: NUBP1 (Nucleotide Binding Protein 1 (NUBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUBP1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-NUBP1 Antibody (PE)

Binding Specificity: AA 1-311

Purpose: Anti-NUBP1 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NUBP1 recombinant protein (Position: M1-Q311).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NUBP1

Target: NUBP1 (Nucleotide Binding Protein 1 (NUBP1))

Alternative Name: NUBP1

Background:

Background: NUBP1 also known as NBP as is expressed in several tissues with the highest being in the lung and testis. NUBP1 appears to interact with actin and the cytoskeleton and is required for centrosome duplication but it is also need for proper synthesis of iron sulfur proteins and the protein also binds ATP. NUBP1 has roles in cell growth, cellular iron homeostasis, centrosome localization, iron-sulfur cluster assembly, and apolipoprotein modification. NUBP1 is localized to the cytoplasm. Interestingly too, recent research indicates that mutations in NUBP1 in mice lead defects in lung development and eye cataracts, many of which are traced back to NUBP1 role in regulating centrosome dynamics and microtubule organization.

Gene Full Name: NUBP iron-sulfur cluster assembly factor 1, cytosolic

Gene ID: 4682

UniProt: P53384

Pathways: Transition Metal Ion Homeostasis