NUBP1 antibody (AA 1-311)
Quick Overview for NUBP1 antibody (AA 1-311) (ABIN8017552)
Target
See all NUBP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
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Binding Specificity
- AA 1-311
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Purpose
- Anti-NUBP1 Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Characteristics
- Anti-NUBP1 Antibody. Tested in ELISA, Flow Cytometry, IF, ICC, IHC, WB applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human NUBP1 recombinant protein (Position: M1-Q311).
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Isotype
- IgG
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Application Notes
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Expiry Date
- 12 months
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- NUBP1 (Nucleotide Binding Protein 1 (NUBP1))
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Alternative Name
- NUBP1
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Background
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Background: NUBP1 also known as NBP as is expressed in several tissues with the highest being in the lung and testis. NUBP1 appears to interact with actin and the cytoskeleton and is required for centrosome duplication but it is also need for proper synthesis of iron sulfur proteins and the protein also binds ATP. NUBP1 has roles in cell growth, cellular iron homeostasis, centrosome localization, iron-sulfur cluster assembly, and apolipoprotein modification. NUBP1 is localized to the cytoplasm. Interestingly too, recent research indicates that mutations in NUBP1 in mice lead defects in lung development and eye cataracts, many of which are traced back to NUBP1 role in regulating centrosome dynamics and microtubule organization.
Gene Full Name: NUBP iron-sulfur cluster assembly factor 1, cytosolic
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Molecular Weight
- 35 kDa
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Gene ID
- 4682
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UniProt
- P53384
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Pathways
- Transition Metal Ion Homeostasis
Target
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