NUMBL antibody (AA 336-537) (Biotin)

Catalog No. ABIN8017795

The Biotin-conjugated Rabbit Polyclonal anti-NUMBL antibody (ABIN8017795) specifically detects NUMBL in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NUMBL antibody (AA 336-537) (Biotin) (ABIN8017795)

Target: NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUMBL antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NUMBL Antibody (Biotin)

Binding Specificity: AA 336-537

Purpose: Anti-NUMBL Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human NUMBL shares 91.1%,89.4% amino acid (aa) sequence identity with mouse,rat NUMBL,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NUMBL recombinant protein (Position: R336-A537). Human NUMBL shares 91.1% and 89.4% amino acid (aa) sequence identity with mouse and rat NUMBL, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NUMBL

Target: NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))

Alternative Name: NUMBL

Background:

Background: Numb-like protein is a protein that in humans is encoded by the NUMBL gene. NUMBL [numb (drosophila) homolog-like] is functionally related to NUMB, a protein that plays an essential role in the determination of cell fate for sensory organ and neural development. Polyglutamine repeats in the NUMBL gene have been associated with schizophrenia in two unrelated populations. Alternate names for NUMBL include NBL, CAG3A, CTG3a, NUMBR, TNRC23, and NUMBLIKE.

Gene Full Name: NUMB like endocytic adaptor protein

Gene ID: 9253

UniProt: Q9Y6R0

Pathways: Cell-Cell Junction Organization