OMG antibody (N-Term)

Catalog No. ABIN8017992

The Rabbit Polyclonal anti-OMG antibody is suitable to detect OMG in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for OMG antibody (N-Term) (ABIN8017992)

Target: OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OMG antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-OMG Antibody

Binding Specificity: N-Term

Purpose: Anti-Oligodendrocyte myelin glycoprotein/OMG Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related mouse sequence by two amino acids.

Characteristics: Anti-Oligodendrocyte myelin glycoprotein/OMG Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human OMG, different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for OMG

Target: OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

Alternative Name: OMG

Background:

Background: Oligodendrocyte-myelin glycoprotein is a protein that in humans is encoded by the OMG gene. This gene is mapped to 17q11-q12. OMG, like neurofibromin (NF1), has growth suppressive effects and downregulates mitogenic signaling pathways closely related to those influenced by neurofibromin. Overexpression of OMG alters mitogenic signaling in fibroblasts. Cells overexpressing OMG grow more slowly in serum compared to controls and show a partial G1 block upon cell cycle analysis.

Gene Full Name: oligodendrocyte myelin glycoprotein

Molecular Weight: 50 kDa

Gene ID: 4974

UniProt: P23515

Pathways: Neurotrophin Signaling Pathway, Regulation of Cell Size