OLIG1 antibody (N-Term) (Biotin)

Catalog No. ABIN8018004

The Rabbit Polyclonal anti-OLIG1 antibody is suitable to detect OLIG1 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for OLIG1 antibody (N-Term) (Biotin) (ABIN8018004)

Target: OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OLIG1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-OLIG1 Antibody (Biotin)

Binding Specificity: N-Term

Purpose: Anti-Olig1 Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse,rat sequences by four amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Olig1, different from the related mouse and rat sequences by four amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for OLIG1

Target: OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))

Alternative Name: OLIG1

Background:

Background: Oligodendrocyte transcription factor 1 (OLIG1), also known as class B basic helix-loop-helix protein 6 (BHLHB6) is a protein that in humans is encoded by the OLIG1 gene. This gene is mapped to 21q22.11. This gene is a member of the oligodendrocyte lineage gene family which encodes basic helix-loop-helix transcription factors. Studies in mice show that it is coexpressed with Olig2 in neural progenitors, and has a role in the development and maturation of oligodendrocytes. OLIG1 gene promotes formation and maturation of oligodendrocytes, especially within the brain. It cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube.

Gene Full Name: oligodendrocyte transcription factor 1

Sequence Similarities: Contains 1 bHLH (basic helix-loop-helix) domain.

Gene ID: 116448

UniProt: Q8TAK6