OFD1 antibody (C-Term) (Fluoro647)

Catalog No. ABIN8018321

This Rabbit Polyclonal antibody specifically detects OFD1 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for OFD1 antibody (C-Term) (Fluoro647) (ABIN8018321)

Target: OFD1 (Oral-Facial-Digital Syndrome 1 (OFD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OFD1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-OFD1 Antibody (Fluoro647)

Binding Specificity: C-Term

Purpose: Anti-OFD1 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human OFD1, which shares 75.9% and 86.2% amino acid (aa) sequence identity with mouse and rat OFD1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for OFD1

Target: OFD1 (Oral-Facial-Digital Syndrome 1 (OFD1))

Alternative Name: OFD1

Background:

Background: Oral-facial-digital syndrome 1 protein is a protein that in humans is encoded by the OFD1 gene. This gene is mapped to Xp22.2. This gene is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not subject to X inactivation. Mutations in this gene are associated with oral-facial-digital syndrome type I and Simpson-Golabi-Behmel syndrome type 2. Many pseudogenes have been identified, a single pseudogene is found on chromosome 5 while as many as fifteen have been found on the Y chromosome.

Gene Full Name: OFD1 centriole and centriolar satellite protein

Gene ID: 8481

UniProt: O75665

Pathways: M Phase