OSCAR antibody (AA 19-282)

Catalog No. ABIN8018534

This Rabbit Polyclonal antibody specifically detects OSCAR in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for OSCAR antibody (AA 19-282) (ABIN8018534)

Target: OSCAR (Osteoclast Associated Receptor (OSCAR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OSCAR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-OSCAR Antibody

Binding Specificity: AA 19-282

Purpose: Anti-OSCAR Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human OSCAR shares 77.3% amino acid (aa) sequence identity with mouse OSCAR.

Characteristics: Anti-OSCAR Antibody. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human OSCAR recombinant protein (Position: D19-V282). Human OSCAR shares 77.3% amino acid (aa) sequence identity with mouse OSCAR.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for OSCAR

Target: OSCAR (Osteoclast Associated Receptor (OSCAR))

Alternative Name: OSCAR

Background:

Background: Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: osteoclast associated Ig-like receptor

Molecular Weight: 30 kDa

Gene ID: 126014

UniProt: Q8IYS5