Glycogen Synthase 2 antibody (AA 621-703) (HRP)

Catalog No. ABIN752182

This Rabbit Polyclonal antibody specifically detects Glycogen Synthase 2 in ELISA, WB, IHC (fro), IHC (p). It exhibits reactivity toward Mouse, Pig.

Quick Overview for Glycogen Synthase 2 antibody (AA 621-703) (HRP) (ABIN752182)

Target: Glycogen Synthase 2 (GYS2) (Glycogen Synthase 2, Liver (GYS2))

Reactivity: Mouse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glycogen Synthase 2 antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Glycogen Synthase 2 Antibody (HRP)

Binding Specificity: AA 621-703

Cross-Reactivity: Mouse, Pig

Predicted Reactivity: Human,Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Glycogen synthase 2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Glycogen Synthase 2

Target: Glycogen Synthase 2 (GYS2) (Glycogen Synthase 2, Liver (GYS2))

Alternative Name: Glycogen synthase 2

Background:

Synonyms: Glycogen starch synthase liver, Glycogen starch synthase liver, EC 2.4.1.11, Glycogen synthase 2 liver, GYS2, GYS2_HUMAN.

Background: Glycogen synthase catalyzes the rate-limiting step in glycogen synthesis. Its activity is regulated by a complex phosphorylation-dephosphorylation mechanism and by allosteric stimulators and inhibitors. Two isozymes of synthase, a skeletal muscle type (Glycogen synthase 1 - GYS1) and a liver type (Glycogen synthase 2 - GYS2), have been identified.

Gene ID: 2998

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process