OTUD5 antibody (AA 168-555)

Catalog No. ABIN8018644

The Rabbit Polyclonal anti-OTUD5 antibody (ABIN8018644) specifically detects OTUD5 in WB, ELISA, IF and ICC. The antibody is reactive with Human and Rat samples.

Quick Overview for OTUD5 antibody (AA 168-555) (ABIN8018644)

Target: OTUD5 (OTU Domain Containing 5 (OTUD5))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OTUD5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-OTUD5 Antibody

Binding Specificity: AA 168-555

Purpose: Anti-OTUD5 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human OTUD5 shares 98.2%,98.5% amino acid (aa) sequence identity with mouse,rat OTUD5,respectively.

Characteristics: Anti-OTUD5 Antibody. Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human OTUD5 recombinant protein (Position: R168-D555). Human OTUD5 shares 98.2% and 98.5% amino acid (aa) sequence identity with mouse and rat OTUD5, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for OTUD5

Target: OTUD5 (OTU Domain Containing 5 (OTUD5))

Alternative Name: OTUD5

Background:

Background: OTU deubiquitinase 5 is a protein that in humans is encoded by the OTUD5 gene. This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Full Name: OTU deubiquitinase 5

Molecular Weight: 75 kDa

Gene ID: 55593

UniProt: Q96G74