Fibrillarin antibody (AA 81-180) (HRP)

Catalog No. ABIN752317

This Rabbit Polyclonal antibody specifically detects Fibrillarin in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Fibrillarin antibody (AA 81-180) (HRP) (ABIN752317)

Target: Fibrillarin (FBL)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibrillarin antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA

Product Details anti-Fibrillarin Antibody (HRP)

Binding Specificity: AA 81-180

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Fibrillarin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Fibrillarin

Target: Fibrillarin (FBL)

Alternative Name: Fibrillarin

Background:

Synonyms: 34 kD nucleolar scleroderma antigen, 34 kDa nucleolar scleroderma antigen, 34-kD nucleolar scleroderma antigen, FBL, FBRL_HUMAN, FIB, FIB1, FLRN, Nop1p, RNU3IP1, rRNA 2' O methyltransferase fibrillarin, rRNA 2''-O-methyltransferase fibrillarin, rRNA 2'-O-methyltransferase fibrillarin.

Background: Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

Gene ID: 2091

Pathways: Ribonucleoside Biosynthetic Process