PDLIM4 antibody (AA 137-271) (Fluoro647)

Catalog No. ABIN8019936

The Rabbit Polyclonal anti-PDLIM4 antibody is suitable to detect PDLIM4 in samples from Human. It has been validated for FACS.

Quick Overview for PDLIM4 antibody (AA 137-271) (Fluoro647) (ABIN8019936)

Target: PDLIM4 (PDZ and LIM Domain 4 (PDLIM4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDLIM4 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-PDLIM4 Antibody (Fluoro647)

Binding Specificity: AA 137-271

Purpose: Anti-PDLIM4 Antibody Fluoro647 Conjugated

Predicted Reactivity: Human PDLIM4 shares 91.2%,89% amino acid (aa) sequence identity with mouse,rat PDLIM4,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PDLIM4 recombinant protein (Position: Y137-D271). Human PDLIM4 shares 91.2% and 89% amino acid (aa) sequence identity with mouse and rat PDLIM4, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PDLIM4

Target: PDLIM4 (PDZ and LIM Domain 4 (PDLIM4))

Alternative Name: PDLIM4

Background:

Background: PDZ and LIM domain protein 4 is a protein that in humans is encoded by the PDLIM4 gene. RIL, also known as PDLIM4 is a putative tumor suppressor gene. RIL is transcriptionally repressed by hypermethylation in a variety of tumors including breast and prostate. The difference in methylation status of RIL between normal and cancerous tissues is being investigated as to determine the use of RIL as a potential biomarker. Two isoforms of human RIL one have been identified.

Gene Full Name: PDZ and LIM domain 4

Gene ID: 8572

UniProt: P50479